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NeuroCONCISE

Consciousness assessment in disorders of consciousness, enablement in spinal injury and growing the UK neurotechnology sector.

Full Case Study

Impact

Ulster has significantly improved patient outcomes, stimulated the UK neurotechnology sector and promoted knowledge exchange arising from the University’s AI for brain-computer interface (BCI) research. Impacts include:

  • Establishing non-subjective evidence of consciousness in brain-injured patients with prolonged disorders of consciousness with specific beneficial, life-changing outcomes and leading to a national neurotechnology trial with 17 hospitals
  • Influencing two medico-legal High Court cases resulting in substantial compensation for brain-injured victims
  • Enabling a spinal-injured person to compete against other teams from around the world as a Cybathlete at Cybathlon 2016, 2019 (BCI series) and 2020
  • Creation of a spinout company, NeuroCONCISE Ltd (Nov 2016), employing 5 people, to commercialise Ulster BCI research
  • Informing national reports that influenced the establishment of the KTN Neurotechnology Innovation Network and the UK roadmap for neurotechnology
  • Research Context 

    Since 2003 neurotechnology and brain-computer interface (BCI) R&D at Ulster has led to the development of advanced award-winning algorithms, software and hardware for translating brain activity recorded non-invasively (electroencephalography (EEG)) into control signals to enable people to communicate and interact with technology without moving and to assess awareness/consciousness following brain injury. Significant research advances that underpin the impacts are clustered in three main topics:

    • Design of award-winning AI and algorithms to translate brain activity into control signals
    • Design of advanced neurofeedback technologies for disabled users
    • Technology trials with patients
  • Sources To Corroborate 
    • Parliamentary report on Research and Development Work Relating to Assistive Technology 2011 to 2012.
    • Nuffield Council on Bioethics report on Novel Neurotechnology: Intervening in the Brain, 2013. A family involved in Ulster trials is quoted (5.2, p.107).
    • Testimony from the KTN Knowledge Transfer Manager Emerging Technologies who led the establishment of the KTN Neurotechnology Innovation.
    • Testimony from family of patient E; High Court Report [2015] IEHC 752 for patient E.
    • Testimony from family of patient S; testimony from legal team of patient S following successful High Court case.
    • Awards certificates: International BCI Research award competition 2015 Top 10 nomination certificate; IEEE Computational Intellig. Soc. Outstanding Doctoral Dissertation Award, 2008; International Neural Network Society Young Investigator of the Year Award, 2011; IET Innovation awards best start-up category winner 2018; IET and E&T Innovation of the Year Award 2018.
    • Testimony from clinical partners at the National Rehabilitation Hospital.
    • Testimony of patient O who competed at the Cybathlon competition 2016, 2019 and 2020.
    • Testimony from organisers of the Cybathlon 2016, 2019 and 2020.
    • NeuroCONCISE company; NeuroCONCISE investment profile; NeuroCONCISE Overview and Product brochure; NeuroCONCISE Management accounts to 31 Dec 2020
  • Dissemination Activities 

Contributors

11. Computer Science and Informatics

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