Enhancing Health Literacy and Medication Management in Older People Living with Frailty: A Comprehensive Approach to Deprescribing

Apply and key information  

Summary

Motivation:

The ageing population in Northern Ireland faces significant challenges related to health literacy, frailty, and polypharmacy. As individuals age, they often accumulate multiple chronic conditions, leading to complex medication regimens. Low health literacy among older adults can exacerbate issues with medication adherence and understanding of health information. Additionally, frailty in this population increases vulnerability to adverse drug events. There is a pressing need to address these interconnected issues to improve health outcomes and quality of life for older adults in Northern Ireland.

Underlying aim:

This project aims to investigate the relationship between health literacy, frailty status, and medication use among older people living with frailty in Northern Ireland. It will focus on identifying opportunities for deprescribing and optimising medication regimens.

Specific Objectives:

  1. Assess health literacy levels and frailty status among older people living with frailty in Northern Ireland using validated tools and standardised assessments.
  2. Conduct a comprehensive medication review for a sample of older people living with frailty, identifying potentially inappropriate medications using validated criteria.
  3. Investigate the relationships between health literacy levels, frailty status, and medication adherence.
  4. Develop, test and evaluate the effectiveness of a patient-centred intervention that combines health literacy education, frailty assessment, and medication optimisation strategies, including deprescribing where appropriate.

Methods: A mixed-methods approach, including:

  • Cross-sectional survey to assess health literacy and outcome measures related to quality use of medicines.
  • Clinical assessments for frailty and medication review adopting the Scottish seven steps for medicines review and the impact tool
  • Qualitative interviews with a subset of participants to explore their experiences and perspectives on frailty, medication use and deprescribing
  • Randomised controlled trial to test the effectiveness of the developed intervention

Impact statement:

This research has the potential to significantly improve the health and well-being of older people living with frailty in Northern Ireland by addressing the critical intersection of health literacy, frailty, and medication management. By developing evidence-based strategies to enhance health literacy and optimise medication use in frail older adults, we can reduce the risks associated with polypharmacy, improve patient understanding and adherence to treatment plans, and potentially improve clinical outcomes. The findings from this study will inform healthcare policy and practice, providing a foundation for more personalised and effective care for older adults. Moreover, the developed intervention could serve as a model for similar initiatives in other regions, contributing to the global effort to improve care for ageing populations.

Essential criteria

Applicants should hold, or expect to obtain, a First or Upper Second Class Honours Degree in a subject relevant to the proposed area of study.

We may also consider applications from those who hold equivalent qualifications, for example, a Lower Second Class Honours Degree plus a Master’s Degree with Distinction.

In exceptional circumstances, the University may consider a portfolio of evidence from applicants who have appropriate professional experience which is equivalent to the learning outcomes of an Honours degree in lieu of academic qualifications.

  • Sound understanding of subject area as evidenced by a comprehensive research proposal
  • A comprehensive and articulate personal statement

Desirable Criteria

If the University receives a large number of applicants for the project, the following desirable criteria may be applied to shortlist applicants for interview.

  • First Class Honours (1st) Degree
  • Completion of Masters at a level equivalent to commendation or distinction at Ulster
  • Practice-based research experience and/or dissemination
  • Experience using research methods or other approaches relevant to the subject domain
  • Work experience relevant to the proposed project
  • Publications record appropriate to career stage
  • Experience of presentation of research findings

Equal Opportunities

The University is an equal opportunities employer and welcomes applicants from all sections of the community, particularly from those with disabilities.

Appointment will be made on merit.

Funding and eligibility

Recommended reading

  1. Etherton-Beer, C. et al. (2023). Deprescribing to optimise health outcomes for frail older people: a double-blind placebo-controlled randomised controlled trial—outcomes of the Opti-med study. Age and ageing, 52(5), afad081.
  2. Geboers, B., et al. (2018). Health literacy among older adults is associated with their 10-years’ cognitive functioning and decline-the Doetinchem Cohort Study. BMC geriatrics18, 1-7.
  3. Gillespie, R., Mullan, J., & Harrison, L. (2023). Exploring Older Adult Health Literacy in the Day-to-Day Management of Polypharmacy and Making Decisions About Deprescribing: A Mixed Methods Study. HLRP: Health Literacy Research and Practice, 7(1), e14-e25.
  4. Hubbard, R. E. et al. (2017). Frailty status at admission to hospital predicts multiple adverse outcomes. Age and ageing, 46(5), 801-806.
  5. Lyne S (2023) Benefits of deprescribing for older people with frailty and polypharmacy: part two. Nursing Older People. doi: 10.7748/nop.2023.e1449

The Doctoral College at Ulster University

Key dates

Submission deadline
Monday 31 March 2025
04:00PM

Interview Date
April 2025

Preferred student start date
15 September 2025

Applying

Apply Online  

Contact supervisor

Dr Mohamed Elnaem

Other supervisors

  •  Ahmed Abuelhana
  • Jayne Agnew, Consultant Pharmacist, Southern Trust , HSCNI and Carmel Darcy, Consultant Pharmacist, Western Trust, HSCNI