Development of a biomedical sensor platform as a health monitoring tool to improve the quality of life of ostomates

Summary

Stoma surgery is a lifesaving intervention for those suffering from cancer and inflammatory bowel disease and, worldwide, it has been estimated that there are over 3 million people with a stoma (200,000 in the UK). While a stoma can greatly improve quality of life (QoL), it can give rise to electrolyte disorders, dehydration and peristomal skin disorders.  Previous studies have suggested that metabolism, nutrient absorption and intestinal microbiota can affect not only an ostomate’s QoL but also the performance of the collecting pouch system. At present, there is a lack of high-quality nutritional studies and supplementation guidelines for those with a stoma. A better understanding of the various physiological-nutrition-microbiome interactions is required to improve the management of the underlying diseases and enhance overall QoL. Key to unravelling these relationships is the development of new, non-invasive sensing technologies that can monitor the biochemical flux within the stomal output. The proposed project takes an interdisciplinary approach to the design and characterisation of wearable / pouch sensors that could ultimately provide a molecular diagnostic profile that could allow more timely and targeted interventions to be made that maintain ostomate well-being.

The project combines engineering with gastrointestinal health and the team are looking for a candidate with a background in engineering, chemistry, biochemistry or related science. The project is sponsored and supported by Eakin Healthcare Ltd and this collaborative partnership aims to explore and subsequently bring to market novel sensing and monitoring technologies that improve the lives of ostomates.

Essential criteria

Applicants should hold, or expect to obtain, a First or Upper Second Class Honours Degree in a subject relevant to the proposed area of study.

We may also consider applications from those who hold equivalent qualifications, for example, a Lower Second Class Honours Degree plus a Master’s Degree with Distinction.

In exceptional circumstances, the University may consider a portfolio of evidence from applicants who have appropriate professional experience which is equivalent to the learning outcomes of an Honours degree in lieu of academic qualifications.

• A comprehensive and articulate personal statement

Equal Opportunities

The University is an equal opportunities employer and welcomes applicants from all sections of the community, particularly from those with disabilities.

Appointment will be made on merit.

Funding and eligibility

This project is funded by:

• DfE CDP Award in collaboration with Eakin Healthcare

This CDP PhD studentship offers an annual non-taxable maintenance grant of approx. £19,500 (plus an additional annual stipend top-up of £3000 incrementing to £5000 at year 3). The grant covers three years of tuition fees (worth over £14,000) and provides extensive support for research training and project running costs.

To be eligible for this scholarships, applicants must meet the following criteria:

• Be a UK National, or

• Have settled status, or

• Have pre-settled status, or

• Have indefinite leave to remain or enter, or

• be an Irish National

Applicants should also meet the residency criteria which requires that they have lived in the EEA, Switzerland, the UK or Gibraltar for at least the three years preceding the start date of the research degree programme.

Applicants who already hold a doctoral degree or who have been registered on a programme of research leading to the award of a doctoral degree on a full-time basis for more than one year (or part-time equivalent) are NOT eligible to apply for an award.

Due consideration should be given to financing your studies.